Yujie Xu Professor

Academic History:

B.S., Suzhou Medical College, Dept. of Radiation Medicine,

Ph.D., Soochow University, School of Radiation Medicine and Protection,

Professor, Soochow University, SKLRMP, 2018-

Research Interests:

 ①The screening of new targeting site for molecular imaging and therapy, and developing of the special radiopharmaceuticals targeting to the EGFR overexpressed cancer  by the receptor-ligand recognition as well as Ag-Ab recognition.

 ②Research and development of new radiation protection materials for lead-free protective gloves used in clinical interventional diagnosis and treatment.

Research Experience and Accomplishments:

 ①Research and development of the special nanoparticle delivery to the cell nucleus as the scavenger of the free radicals induced by acute radiation exposure. (NSFC,30270441, 2003-2005, NSFC,30970873,2010-2012).

 ②Research and development of the special nanoparticle chelating agent of the internal contamination of radionuclides( such as ⁹⁰Sr).

 ③Research and development of the special radiopharmaceuticals targeting to the EGFR overexpressed cancer , and fluorescence probe for cancer cell imaging. (NSFC, 11475124, 2015-2018)

Academic Awards and Honors:

2014, Zhan-shan Yang, Shu-Yu Zhang, Yujie Xu, Jian-Ping Cao, Nan-kang Zhu, Quan-shui Shu: The study acute of radiation injury treatment technology for nuclear and radiological emergency. The Second Prize of Technological Innovation awarded by China Ministry of Education.Certificate No2014-167.

2014, Zhan-shan Yang, Shu-Yu Zhang,Yujie Xu, Jian-Ping Cao, Dao-ben Hua,Nan-kang Zhu, The research of the new treatment technology to acute radiation injury.  The Second Prize of Technological Innovation awarded by China Nuclear Energy Association.Certificate No2014HNJ13R-03.

2014, Zhan-shan Yang,Yujie Xu, Shu-Yu Zhang, Jian-Ping Cao, Dao-ben Hua, The Biological Effect of Ionizing Radiation and the new Prevention and treatment technology of radiation injury. The Second Prize of Science and Technology Progress awarded by  Suzhou City government.Certificate No 2-18-2.

Main Publications:

1、Wu M X#, Wei X# , Wei Y F , Sun R，Xu Y J*, Ge J F*.. A highly efficient fluorescent probe based on tetrahydroxanthylium−coumarin for detection bisulfite in mitochondria. Analytical methods, 2019, 11(34):4334-4340（IF 2.070）

2、Chen Y#, Wei X# , Sun R , Xu Y J*, Ge J F*. Synthesis of azonia cyanine derivatives as NIR fluorescent probes for nucleic acid detection and cell imaging. Analytical methods, 2019, 11(28):3523-3531（IF 2.070）

3、Wei-Jin Zhu,Jin-Yun Niu,Ru Sun,Yu-Jie Xu*,Jian-Feng Ge*. The improvement of lysosome targetability with oligoethyleneoxy chains linked benzo[a]phenoxazine. Bioorganic & Medicinal Chemistry Letters.28(15):2018, 2953-295(IF 2.442 Correspondence author)/4

4、Tian C , Niu J Y , Wei X , Xu Y*，Zhang L*, Cheng Z*, Zhu X. Construction of dual-functional polymer nanomaterials with near-infrared fluorescence imaging and polymer prodrug by RAFT mediated aqueous dispersion polymerization[J]. Nanoscale, 2018:10.10277-10287(IF7.8，Correspondence author）

5、Wei-Jin Zhu‡, Jin-Yun Niu‡, Dan-Dan He, Ru Sun, Yu-Jie Xu *, Jian-Feng Ge *，Near-infrared pH probes based on phenoxazinium connecting with nitrophenyl and pyridinyl groups. Dyes and Pigments. 2018,149: 481-490(IF3.473，Correspondence author)

6、Yang，Ling‡；Niu，Jinyun‡；Zhan，Yanhua；Xu，Yujie*；Sun， Ru； and Ge，Jianfeng *；Fluorescence Responses of the Protonation and Deprotonation Processes between Phenolate and Phenol within Rosamine. Chinese Journal of Chemistry.  2018 , 36 (1):42-46 (IF1.852，Correspondence author)

7、Chen Y, Wei X R,  Sun R*，Xu Y J*, Ge J F*. The fluorescent biomarkers for lipid droplets with quinolone-coumarin unit[J]. Organic & Biomolecular Chemistry, 2018, 16(41)：7619-7625，(IF 3.423)

8、Zhan,Yan-Hua ; Sun, Ru ; Zhu, Wei-Jin ; Xu, Yu-Jie* ; Ge, Jian-Feng*. An oxazine-based near-infrared fluorescent probefor selective in cellular imaging of exogenous nitrite. Sensors &Actuators: B. Chemical, 2017,240, 1283-1290. (Correspondence author）

9、Liu,Xiaodong ; Chen, Bizheng; Li, Xiaojun; Zhang, Lifen ; Xu, Yujie *;   Liu Zhuang*; Cheng,Zhenping *and  Xiulin Zhu. Self-assembly of BODIPY based pH-sensitivenear-infrared polymeric micelles for drug controlled delivery and fluorescenceimaging applications. Nanoscale. 2015，7(39):16399-416. (IF 7.394,1 Correspondence author,）

10、Liu，Xiao-Dong ; Fan，Chen;  Sun，Ru;  Xu, Yu-Jie *; Ge ,Jian-Feng *.Nile-redand Nile-blue-based near-infrared fluorescent probes for in-cellulo imaging ofhydrogen sulfide. Anal Bioanal Chem 2014, 406:7059–7070 (PAPER INFOREFRONT, IF 3.7, Correspondence author)

11、Yu-Jie Xu, Min Liu, Bai-xie Yang, Jun-jie Sun: The Preparation and application of fullerol (C60(OH)24)  Solid lipid nanoparticles. China Patent ,ZL201110439349.1，2014.6

12、Yu-Jie Xu , Jing-dong Wang, Radiation protective gloves and its making method. China Potent, ZL201510969259.1, 2017.12.22

 …

Contact:

Phone: 13913518258

E-mail:dbnm@suda.edu.cn; xuyuj@hotmail.com

Fax:0512-65880061

Office:0210-65880061